Avalide

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Anita Deswal, MD, MPH

  • Associate Professor of Medicine
  • Section of Cardiology and Winters
  • Center for Heart Failure Research
  • Michael E. DeBakey VA Medical Center and Baylor College of Medicine
  • Houston, Texas

Manipulating the metabolic response to Guidelines for the management of growth failure in childhood infiammatory injury heart attack survival rate order 162.5 mg avalide otc. World Rev [80] Gerasimidis K pulse pressure 55 mmhg generic avalide 162.5 mg line, Edwards C prehypertension 120 80 order avalide 162.5 mg online, Stefanowicz F arteria tibialis anterior discount avalide 162.5mg on line, Galloway P, McGrogan P, Duncan A, Nutr Diet 2013;106:156e61. Clinical dilemmas in infiammatory bowel disease, new epiphenomenon of the systemic infiammatory response. Vitamin and zinc status preChanges in energy metabolism after induction therapy in patients with setreatment and posttreatment in patients with infiammatory bowel disease. Energy expenditure and nitroagnose and efficiently treat iron deficiency anaemia in infiammatory bowel gen balance. Pediatr Int 2015;57: the diagnosis and management of iron deficiency and anaemia in infiam290e4. Measured versus predicted [92] Bonovas S, Fiorino G, Allocca M, Lytras T, Tsantes A, Peyrin-Biroulet L, et al. Clin Nutr Intravenous versus oral iron for the treatment of anaemia in infiammatory 2005;24:1047e55. Infiamm Bowel Dis a randomized controlled trial on ferric carboxymaltose for iron deficiency 2011;17:1587e93. Dig Dis Sci Randomised, double-blind, placebo-controlled trial of fructo1996;41:1754e9. Malabsorption is a major contributor to [97] Borrelli O, Cordischi L, Cirulli M, Paganelli M, Labalestra V, Uccini S, et al. Nutrition 2006;22: Polymeric diet alone versus corticosteroids in the treatment of active pedi855e9. Crit Rev Fat composition may be a clue to explain the primary therapeutic effect of Food Sci Nutr 2015;10:1370e8. Guidelines for the management of infiamma[113] Fuchigami T, Ohgushi H, Imamura K, Yao T, Omae T, Watanabe H, et al. The vitamin D status in infiammatory [146] Dziechciarz P, Horvath A, Shamir R, Szajewska H. Gut 2014;63: [150] Fuchssteiner H, Nigl K, Mayer A, Kristensen B, Platzer R, Brunner B, et al. A randomized, placebo-controlled trial of calcium supplementation for [151] August D, Teitelbaum D, Albina J, Bothe A, Guenter P, Heitkemper M, et al. Effect of enterocoated cholestyramine on bowel habit after ileal J Gastroenterol 2005;40(Suppl 16):25e31. Society of Critical Care medicine rhea with ox bile in an ileectomy patient with residual colon. Enteric hyperoxaluria: dependence [155] Nakahigashi M, Yamamoto T, Sacco R, Hanai H, Kobayashi F. Aliment Pharmacol Ther [159] Takagi S, Utsunomiya K, Kuriyama S, Yokoyama H, Takahashi S, Iwabuchi M, 2002;16:1131e5. Aliment Pharmacol Ther European evidence-based consensus on the diagnosis and management of 2006;24:1333e134012. J Crohn Colitis 2012;6: [160] Esaki M, Matsumoto T, Nakamura S, Yada S, Fujisawa K, Jo Y, et al. Does preoperative total parenteral nutrition in patients with ulcerative co[161] Yamamoto T, Shiraki M, Nakahigashi M, Umegae S, Matsumoto K. Perioperative parenteral nutrition in adults with infiammatory prospective cohort study. Consensus review of optimal pericatheter-associated deep venous thrombosis in infiammatory bowel disease. Impact of body mass index and albumin on morbidity and mortality after J Crohns Colitis 2013;7:723e9. Treatment strategies in 135 consecutive patients with enterocutaneous fisNutrition support in clinical practice: review of published data and recomtulas. Nutritional support sored by the National Institutes of Health, American Society for Parenteral and risk factors of appearance of enterocutaneous fistulas. The second European evidence-based Consensus on the diagnosis and tional status on outcome after hip fracture. Advances in nutritional therapy in severely stressed patients receiving thoracic esophagectomy. Nutritional status, nutrition for the management of infiammatory bowel disease in adults. Gut 2011;60: practices and post-operative complications in patients with gastrointestinal 571e607. Nutritional parameters and short term Clinical features and management of duodenal fistula in patients with outcome in arthroplasty. The role of total parenteral nutrition in infiamin lifestyle associated with long-term home parenteral and enteral nutrition. The impact of nutrienterocutaneous fistula: outcome and factors predictive of increased posttional status on the outcome of lung volume reduction surgery: a prospecoperative morbidity. Nutrition as a prognostic indicator in amputanutritional treatment in Crohn disease. Prevalence of malnutrition in gastric cancer patients undergoing gastrecNutrition 2011;27:503e4. Nutritional screening for risk prediction in patients scheduled for tion: a prospective 12 month randomised controlled trial. Fish oil fatty acid supplementation in active dietary supplements in preand postoperative surgical patients: a proulcerative colitis: a double-blind, placebo-controlled, crossover study. Randomized clinical trial of the effects of preoperative and postoperative Dietary patterns and self-reported associations of diet with symptoms of oral nutritional supplements on clinical course and cost of care. Pre-operative nutrition support in patients of patients with infiammatory bowel diseases. Lactose malabsorption in paafter digestive surgery: results of a nine-year experience. Clin Nutr 2002;21: tients with infiammatory bowel disease without activity: would it be 59e65. Lancet 1985;2(8448): Early enteral feeding compared with parenteral nutrition after oesophageal 177e80. Infiuence ribonucleic acid-supplemented diet versus placebo in cancer patients: an of dietary factors on the clinical course of ulcerative colitis: a prospective immunologic evaluation of Impact. Acta Paediatr [224] Bozzetti F, Gavazzi C, Miceli R, Rossi N, Mariani L, Cozzaglio L, et al. World J Gastroenterol 2010;16: parenteral nutrition in the surgical patient: a meta-analysis. Canadian clinical effect of nutritional therapy against postoperative recurrence of Crohn dispractice guidelines for nutrition support in mechanically ventilated, critically ease, with reference to findings determined by intra-operative enteroscopy. Review article: evidence-based dietary advice for colorectal surgery versus later commencement of feeding for postoperative patients with infiammatory bowel disease. Omega-3 fatty acids and infiammatory testinal surgery versus later commencement of feeding: a systematic review bowel diseases a systematic review. N Engl J acute intestinal failure: a position paper from the European society for Med 1996;334:1557e60. Omega-3 free fatty acids for the maintenance of remission in Crohn Surg 2004;74:298e301. The clear liquid diet is no [260] Romano C, Cucchiara S, Barabino A, Annese V, Sferlazzas C. Usefulness of longer a necessity in the routine postoperative management of surgical omega-3 fatty acid supplementation in addition to mesalazine in mainpatients. J Gastrointest Surg 2008;12: [264] Hanai H, Kanauchi O, Mitsuyama K, Andoh A, Takeuchi K, Takayuki I, et al. High amount of dietary fiber not randomized controlled trial of nutritional therapy. Maintaining [294] Duncan H, Buchanan E, Cardigan T, Garrick V, Curtis L, McGrogan P, et al. Impacts of long-term enteral nutrition on clinical and endoscopic Beneficial effects of probiotic bifidobacterium and galacto-oligosaccharide in disease activities and mucosal cytokines during remission in patients with patients with ulcerative colitis: a randomized controlled study.

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Holmium laser versus transurethral resection of the prostate: a randomized prospective trial with 1-year followup arrhythmia facebook purchase avalide in india. Lower urinary tract injury during gynecologic surgery and its detection by intraoperative cystoscopy arteria facialis cheap 162.5 mg avalide amex. Interleukin-8 is a paracrine inducer of fibroblast growth factor 2 blood pressure chart enter numbers cheap avalide 162.5mg visa, a stromal and epithelial growth factor in benign prostatic hyperplasia arrhythmia medication list purchase avalide 162.5 mg. Analysis and reliability of data from 24-hour frequency-volume charts in men with lower urinary tract symptoms due to benign prostatic hyperplasia. Dutasteride improves objective and subjective disease measures in men with benign prostatic hyperplasia and modest or severe prostate enlargement. Accuracy of prostate volume measurements using transrectal multiplanar three-dimensional sonography. Hemodynamic interaction study between the alpha1blocker alfuzosin and the phosphodiesterase-5 inhibitor tadalafil in middle-aged healthy male subjects. Combined effect of terazosin and finasteride on apoptosis, cell proliferation, and transforming growth factor-beta expression in benign prostatic hyperplasia. Induction of apoptosis in human prostate stromal cells by 4-hydroxytamoxifen: an alternative therapy for benign prostate hyperplasia. Lower urinary tract symptoms and erectile dysfunction are highly prevalent in ageing men. Outcome of transurethral prostatectomy for the palliative management of lower urinary tract symptoms in men with prostate cancer. Case-control prostate cancer screening studies should not exclude subjects with lower urinary tract symptoms. A trial study: the effect of low dose human chorionic gonadotropin on the symptoms of benign prostatic hyperplasia. Re: Transurethral resection of prostate and suprapubic ballistic vesicolithotripsy for benign prostatic hyperplasia with vesical calculi (Kamat et al; J Endourol 2003; 17:505-510) and Per-urethral endoscopic management of bladder stones: does size matter. Retroperitoneal laparoscopic radical nephrectomy and nephroureterectomy and comparison with open surgery. Effect of lower infundibulopelvic angle, lower infundibulum diameter and inferior calyceal length on stone formation. The presence and structure of circulating immune complexes in patients with prostate tumors. Saw palmetto berry extract inhibits cell growth and Cox-2 expression in prostatic cancer cells. Doxazosin gastrointestinal therapeutic system: a review of its use in benign prostatic hyperplasia. Urothelial cancer of the bladder in an area of former coal, iron, and steel industries in Germany: a case-control study. The role of combination therapy for lower urinary tract symptoms secondary to benign prostatic hyperplasia. Initial experience with laparoscopic ipsilateral ureteroureterostomy in infants and children for duplication anomalies of the urinary tract. First-line treatment for symptomatic benign prostatic hyperplasia: is there a particular patient profile for a particular treatment. Tadalafil for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia. A prospective pilot study to validate the management protocol for patients presenting with acute urinary retention: a community-based, nonhospitalised protocol. Periprostatic nerve blockage reduces postoperative analgesic consumption and pain scores of patients undergoing transurethral prostate resection. Comparison of tamsulosin and naftopidil for efficacy and safety in the treatment of benign prostatic hyperplasia: a randomized controlled trial. Positive bladder cooling reflex in patients with bladder outlet obstruction due to benign prostatic hyperplasia. Prognostic value of pressureflow study in surgical treatment of benign prostatic obstruction. Benign hyperplasia of the human prostate is associated with tissue enrichment in chondroitin sulphate of wide size distribution. Predictive factors for nocturia in elderly men: a cross-sectional study in 21 general practices. Evaluation of the fibroblast growth factor system as a potential target for therapy in human prostate cancer. Transurethral ethanol injection therapy for prostatic hyperplasia: 3-year results. Ethanol injection therapy of the prostate for benign prostatic hyperplasia: preliminary report on application of a new technique. Nitric oxide synthases in normal and benign hyperplastic human prostate: immunohistochemistry and molecular biology. Anatomic and metabolic risk factors for nephrolithiasis in patients with autosomal dominant polycystic kidney disease. Primary lower urinary tract reconstruction for nonfunctioning renal moieties associated with obstructing ureteroceles. The performance of routine ultrasonographic screening of pregnancies in the Eurofetus Study. Ureteropyeloscopic diagnosis and treatment of upper urinary tract urothelial malignancies. Complications and early postoperative outcome after open prostatectomy in patients with benign prostatic enlargement: results of a prospective multicenter study. Transurethral microwave thermotherapy: from evidence-based medicine to clinical practice. Application of external microwave thermotherapy in urology: past, present, and future. Efficacy and safety of intraprostatic temperature-controlled microwave thermotherapy in patients with benign prostatic hyperplasia: results of a prospective, open-label, single-center study with 1-year follow-up. Durability of 30-minute high-energy transurethral microwave therapy for treatment of benign prostatic hyperplasia: a study of 213 patients with and without urinary retention. Differences in prostate disease symptoms and visits to the general practitioner among three ethnic groups in New Zealand. Interstitial cystitis: a guide to recognition, evaluation, and management for nurse practitioners. Pigment epithelium-derived factor, a human testis epididymis secretory product, promotes human prostate stromal cell growth in culture. An investigation into the relationship between prostate size, peak urinary flow rate and male erectile dysfunction. Tolerability of once-weekly alendronate in patients with osteoporosis: a randomized, double-blind, placebo-controlled study. A nomogram to classify men with lower urinary tract symptoms using urine flow and noninvasive measurement of bladder pressure. Noninvasive measurement of bladder pressure by controlled inflation of a penile cuff. Experience with the spanner prostatic stent in patients unfit for surgery: an observational study. Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Noninvasive outcome measures of urinary incontinence and lower urinary tract symptoms: a multicenter study of micturition diary and pad tests. The significance of the American Urological Association symptom index score in the evaluation of women with bladder outlet obstruction. Detrusor pressure uroflowmetry studies in women: effect of a 7Fr transurethral catheter. Use of titanium staples during upper tract laparoscopic reconstructive surgery: initial experience. Mammaglobin expression in gynecologic malignancies and malignant effusions detected by nested reverse transcriptase-polymerase chain reaction. Epidemiological survey of benign prostatic hyperplasia and prostatic cancer in China.

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Berger T arteria ductus deferentis purchase generic avalide on-line, Rubner P blood pressure infant normal value order avalide without prescription, Schautzer F heart attack quiz questions generic avalide 162.5 mg free shipping, Egg R blood pressure medication for ptsd buy avalide 162.5mg on-line, Ulmer H, Mayringer I, Dilitz E, Deisenhammer F, & Reindl M (2003) Antimyelin antibodies as a predictor of clinically definite multiple sclerosis after a first demyelinating event. Bernier J, Fournier F, Blais Y, Lombardi P, Chevalier G, & Krzystyniak K (1988) Immunotoxicity of aminocarb. Chemically-induced alterations in sexual and functional development: the wildlife/human connection. Bouma G & Strober W (2003) the immunological and genetic basis of inflammatory bowel disease. Bovenzi M, Barbone F, Betta A, Tommasini M, & Versini W (1995) Scleroderma and occupational exposure. Brostoff J, Blanca M, Boulton P, & Serrano S (1982) Absence of specific IgE antibodies in toxic oil syndrome. Casciola-Rosen L, Wigley F, & Rosen A (1997) Scleroderma autoantigens are uniquely fragmented by metal-catalyzed oxidation reactions: implications for pathogenesis. Chen M, Hemmerich P, & Von Mikecz A (2002) Platinum-induced autoantibodies target nucleoplasmic antigens related to active transcription. Final report of the Subcommittee on Risk Management of the Committee to Co-ordinate Environmental Health and Related Progams. An immunohistochemical study using cryostat sections of the whole knee joint of rat. Brown Norway rats treated with D-penicillamine develop autoantibodies, circulating immune complexes, and disseminated intravascular coagulation. Gaubitz M, Jackisch C, Domschke W, Heindel W, & Pfleiderer B (2002) Silicone breast implants: correlation between implant ruptures, magnetic resonance spectroscopically estimated silicone presence in the liver, antibody status and clinical symptoms. 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Hypponen E (2004) Micronutrients and the risk of type 1 diabetes: vitamin D, vitamin E, and nicotinamide. Iannello S, Camuto M, Cantarella S, Cavaleri A, Ferriero P, Leanza A, Milazzo P, & Belfiore F (2002) Rheumatoid syndrome associated with lung interstitial disorder in a dental technician exposed to ceramic silica dust. Geneva, World Health Organization, International Programme on Chemical Safety (Environmental Health Criteria 180). Karvonen M, Viik-Kajander M, Moltchanova E, Libman I, LaPorte R, & Tuomilehto J (2000) Incidence of childhood type 1 diabetes worldwide. Kirchner J, Stein A, Viel K, & Jacobi V (1997) [Hamman-Rich syndrome in a goldsmith. Korpilahde T, Heliovaara M, Kaipiainen-Seppanen O, Knekt P, & Aho K (2003) Regional differences in Finland in the prevalence of rheumatoid factor in the presence and absence of arthritis. Absence of mature T cells in thymus and periphery of bone marrow transplanted mice treated with cyclosporin A. Kubicka-Muranyi M, Kremer J, Rottmann N, Lubben B, Albers R, Bloksma N, Luhrmann R, & Gleichmann E (1996) Murine systemic autoimmune disease induced by mercuric chloride: T helper cells reacting to self proteins. Langer P, Kocan A, Tajtakova M, Petrik J, Chovancova J, Drobna B, Jursa S, Pavuk M, Koska J, Trnovec T, Sebokova E, & Klimes I (2003) Possible effects of polychlorinated biphenyls and organochlorinated pesticides on the thyroid after long-term exposure to heavy environmental pollution. Lundberg I, Alfredsson L, Plato N, Sverdrup B, Klareskog L, & Kleinau S (1994) Occupation, occupational exposure to chemicals and rheumatological disease. Matheson D, Clarkson T, & Gelfand E (1980) Mercury toxicity (acrodynia) induced by long-term injection of gamma globulin. Mehlhorn J, Enderlein G, Conrad K, & Ziegler V (1999) Analysis for the association between progressive systemic scleroderma, exposure to quartz dust and silicosis in East German uranium mining. 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Adverse effects of long-term systemic vasculitis arrhythmia junctional order genuine avalide on-line, particularly for patients in whom steroid use blood pressure 6050 purchase 162.5 mg avalide free shipping. The multisystem involvement of comorbidities resulting from disease-related end in systemic vasculitis necessitates a multi disciplinary organ damage and immunosuppressive therapy blood pressure jumps around avalide 162.5mg on line. Recent advances in immunosuppressive medications used for the treatment therapy have led to considerably better outcomes in of systemic vasculitis cause serious adverse effects durpatients with vasculitis sheer heart attack avalide 162.5 mg otc. Steroids and cyclophosphamide predispose patients to life-threatening infections. The Authors Cyclophosphamide can cause hemorrhagic cystitis, ovarian and testicular failure, and bladder cancer. Prevalence of coronary artery lesions on the initial echocardiogram in Kawasaki syndrome. Randomized trial of cycloopment of classifcation and diagnostic criteria in systemic vasculitis. Predictive value of antineutrophil cytoplasmic antibodies in small-vessel vasculitis: is the glass half full or half emptyfi Biologic therapy in primary by a novel third-generation enzyme-linked immunosorbent assay. Clinical manifestations of cutaneous vasculitis occur when small and/or medium vessels are involved. Small vessel vasculitis can present as palpable purpura, urticaria, pustules, vesicles, petechiae, or erythema multiforme-like lesions. Signs of medium vessel vasculitis include livedo reticularis, ulcers, subcutaneous nodules, and digital necrosis. Vasculitis can involve any organ system in the body, ranging from skin-limited to systemic disease. Although vasculitis is idiopathic in 50% of cases, common associations include infections, inflammatory diseases, drugs, and malignancy. The management of cutaneous vasculitis is based on four sequential steps: confirming the diagnosis with a skin biopsy, evaluating for systemic disease, determining the cause or association, and treating based on the severity of disease. Keywords Cutaneous vasculitis, leukocytoclastic vasculitis Definition Vasculitis is inflammation of the blood vessel Classification / Etiology wall that leads to various clinical manifestations the classification schemes for the vasculitides depending on which organ systems are involved. Other histologic findings that and small-sized arteries and veins; and small may be seen include extravasated erythrocytes, vessels refer to the arterioles, venules, and granulocytic debris (leukocytoclasis), capillaries. Vasculitis has a wide spectrum of severity, histologic data to classify the vasculitides (Table ranging from skin-limited disease to life1) (1). Approximately 50% of the cutaneous findings of vasculitis depend cases are idiopathic, while infection (15-20%), upon which vessels are primarily involved. The lesions may present as and foodstuff allergens (milk products, gluten) purpura, papules, vesicles or urticaria, and tend have been associated with cutaneous vasculitis to occur in dependent areas, in areas of trauma, (11). The disease often Small and Medium Vessel Vasculitides presents acutely following an upper respiratory tract infection (23). Type I consists of monoclonal IgM self-limited, but chronic renal disease can occur and is always associated with a hematologic in 20-30% of patients with an increased disorder. Type I cryoglobulins lead to vessel incidence in adults compared to children (24). Other less arthralgias, and myalgias, followed by more frequent associations include autoimmune overt signs of vasculitis. Vasculitis of the medium-sized include arthralgias, nephritis, and peripheral intrarenal arteries results in renovascular neuropathy (36). Cutaneous lesions hypocomplementemia (90%), positive include palpable purpura, livedo reticularis, rheumatoid factor (70%), transaminitis (25-40%), ulcers, subcutaneous nodules, and rarely digital and positive anti-nuclear antibodies (20%) (38). The symptoms, signs, and lesions to sample are between 12-24 hours of laboratory findings may be consistent with a age, as lesions less than 12 hours or greater particular systemic vasculitic syndrome, but a than 24 hours old can have a predominantly tissue biopsy (ie. Biopsies taken from nodules vasculitis will have a treatable associated generally have a higher yield than samples taken condition, such as infection, inflammatory from an ulcer edge or livedo. For skin-limited disease, general measures include eliminating causal exposures, rest, leg elevation, avoiding tight-clothing, and keeping warm. For chronic or persistent skin-limited Chung L and Fiorentino D Cutaneous vasculitis. A brief refractory to conventional therapy demonstrated period of high dose oral corticosteroid therapy sustained remission in all patients while B may be required for initial control of severe lymphocytes were absent (69). Recalcitrant cases may available agents targeting cytokines, B cells, T respond to alternate immunosuppressive cells, neutrophils, or complement activation therapies, such as low-dose methotrexate (<25 require further investigation in clinical trials. Hunder G, Arend W, Bloch D, Calabrese therapy includes high dose corticosteroids in L, Fauci A, Fries J. Jennette J, Falk R, Andrassy K, Bacon studied as alternative agents to P, Churg J, Gross W. Nomenclature of systemic cyclophosphamide for induction, maintenance, vasculitides. Gyselbrecht L, DeKeyser F, Ongenae K, contraindications to traditional Naeyaert J, Praet M, Veys E. Blanco R, Martinez-Taboada V, diseases with various etiologic, clinical, and Rodriguez-Valverde V, Garcia-Fuentes M. Such a system, as well associated with infections, immunization, and as further studies to elucidate the pathogenesis antimicrobial drugs. The Biologic agents are currently under investigation mortality of rheumatoid vasculitis compared with for use in the treatment of systemic vasculitides, rheumatoid arthritis. Vasculitis in a mean improvement in Birmingham Vasculitis systemic lupus erythematosus. Ramos-Casals M, Anaya J, Garciablind randomized controlled trial of etanercept in Carrasco M, Rosas J, Bove A, Claver G. Lotti T, Ghersetich I, comacchi C, corticosteroids and cyclophosphamide suggest Jorizzo J. Cutaneous Polyarteritis nodosa, microscopic polyangiitis vasculitis: its relationship to systemic disease. Mills J, Michel B, Bloch D, Calabrese L, Cryoglobulinemia: study of etiologic factors and Hunder G, Arend W. The American College of clinical and immunologic features in 443 patients Rheumatology 1990 criteria for the classification froma single center. Vasculitis associated with glomerulonephritis in a retrospective study of 57 connective tissue disease. Rosas J, Pallares L, Calvo-Alen J, Cervera R, et Antineutrophil cytoplasmic antibodies, abnormal al. Primary Sjogren syndrome: clinical and angiograms and pathologic findings in immunologic disease patterns in a cohort of 400 polyarteritis nodosa and Churg-Strauss patients. Hagen E, Daha M, Hermans J, Andrassy patients with rheumatoid arthritis complicated by K, Csernok E, Gaskin G. Jorizzo J, White W, Wise C, Zanolli M, cytoplasmic antibodies in idiopathic systemic Sherertz E. Plasmapheresis in hypocomplementemic urticarial vasculitis-a antineutrophil cytoplasmic antibodies-associated case report. Booth A, Harper L, Hammad T, Bacon P, in eleven patients with refractory antineutrophil Griffith M, Levy J. Palpable purpura: a manifestation of small vessel vasculitis Chung L and Fiorentino D Cutaneous vasculitis. Cutaneous manifestations of medium vessel vasculitis Fig 4a: Livedo reticularis Chung L and Fiorentino D Cutaneous vasculitis. N Engl J Med 2003;349:160-169 Vasculitis 10 Giant Cell Arteritis Pathogenesis Weyand, C. N Engl J Med 2003;349:160-169 Vasculitis 11 Giant Cell Arteritis Pathogenesis Weyand, C.